Wheat Germ Extract Spermidine Powder

Product Description

What is Spermidine？

Spermidine is a natural polyamine, i.e. an organic molecule involved in multiple essential cellular processes. It is known to be present in virtually all living cells, including plants, bacteria and animals.

Our body produces spermidine naturally, but we also obtain it through food. Its most prominent function is to promote autophagy, a cellular mechanism by which the body eliminates waste, repairs damage and recycles old or defective components. This process is key to maintaining cellular health and preventing aging-related diseases.

In addition to its role in autophagy, spermidine is involved in the regulation of cell growth, DNA stability and protection against oxidative stress, making it a compound of great interest to medical and nutritional science.

Spermidine products on the market are often available as nutritional supplements, typically extracted from germinated wheat. These products are usually sold in capsule form at varying concentrations and are commonly used in anti-aging health programs or cellular health regimens.

Sources of spermidine

Besides the body’s own production of spermidine, spermidine-rich foods and the gut microbiome are considered the most important sources. Polyamines like spermidine can be found in all kinds of food in a wide range of concentrations. A well-known plant source is wheat germ.

Plant and fungal foods are the richest dietary sources of spermidine, with wheat germ, soybeans, and legumes containing concentrations of up to 35 mg/100 g, 18 mg/100 g, and 10 mg/100 g, respectively. Certain mushrooms, including shiitake and king trumpet varieties, contain up to 16 mg/100 g, whereas nuts and seeds offer 5–6 mg/100 g. Vegetables like broccoli, cauliflower, and green pepper, as well as grains like amaranth, are other notable sources of spermidine.

What Is Spermidine Trihydrochloride?

Spermidine trihydrochloride is a stable, highly soluble salt form of the naturally occurring polyamine spermidine, which is present in all living cells. This compound plays a fundamental role in cellular metabolism, proliferation, differentiation, and aging-related processes.

Originally discovered in semen, spermidine is now widely studied in fields ranging from molecular biology to nutritional science and anti-aging research. The trihydrochloride version enhances its solubility and stability, making it suitable for laboratory experiments, pharmaceutical formulations, and industrial applications.

Wheat Germ Extract Spermidine Powder Specification

Health benefits of spermidine

• Spermidine and Ageing

Spermidine has also been associated with supporting healthy ageing. It may help reduce oxidative stress, responsible for damaging important cells, DNA and proteins within the body that can accelerate the ageing process drastically. It also may protect your DNA and preserve the function of mitochondria, which is the ‘powerhouse’ of all of the cells in your body responsible for producing energy.

Through supporting the processes of autophagy and helping preserve crucial cellular interactions, spermidine may work to support anti-ageing by preserving the quality and health of your cells for longer, and reducing damage.

• Spermidine may stimulate Autophagy

One of the most promising benefits of spermidine is its potential to stimulate autophagy. As discussed, autophagy is the process of cleaning and recycling damaged cells.

It becomes less efficient with age, but studies have shown that spermidine may help induce the process of autophagy, so as your body slows this process over time, spermidine steps in to make sure it’s kick-started. In research on yeast, mice and flies, spermidine was linked to longer lifespans and healthier cells.

With improving the autophagy process, this could lead to more graceful ageing and healthier cells within the body for longer.

• Spermidine and Brain Function

Emerging research has also shown that spermidine may help maintain memory and cognitive function in older adults.

In a 3 month long study in 2021, participants who took spermidine daily showed improvements in memory performance compared to those who didn’t. This was measured by participants highlighted as high risk of dementia orally administering a dose of spermidine.

The study showed a clear correlation between spermidine intake and improved cognitive performance in subjects with mild to moderate dementia in the groups treated with a higher dose of spermidine.

This supports the theory that spermidine use over a prolonged amount of time may support the delay of cognitive decline.

• Spermidine and Heart Health

A study in 2016 found that people who eat more spermidine-rich foods have a lower risk of heart-related illnesses.

Research carried out on mice found that spermidine has beneficial effects on the health and lifespan on mice, due to cardiovascular health improvement[4].

Whilst this research is carried out on animal models, there are also epidemiological studies that support similar results on humans.

• Spermidine and Gut Health

There is early evidence that spermidine could support a healthy gut microbiome and reduce inflammation in the digestive system.

When tested on mice, spermidine resulted in improved gut barrier integrity and gut microbiota function, making it a promising insight for potential gut health improvement.

• Spermidine could support weight management

In studies involving animals, spermidine has been linked to a better metabolism and less fat build-up. With research showing protection against diet-induced obesity in some animal models.

It also points to improvements in insulin sensitivity, which plays a big role in how your body handles sugar.

While human studies are still ongoing, these provide a positive insight into how spermidine could play a promising role in weight management.

Why Choose Our Spermine Powder?

• Premium Quality & High Purity

Sourced from top-grade raw materials with advanced purification technology. High assay, low impurities, consistent quality, and reliable performance for your formulations.

• 26 Years of Professional Expertise

26 years focused on R&D and manufacturing of functional raw powder. Mature production process, rich industry experience, and deep understanding of global market standards.

• Stable Supply & On-Time Delivery

Large-scale production capacity + reliable raw material supply chain. Steady long-term supply, sufficient inventory, and punctual delivery for bulk orders.

• Strict Quality Control System

Full-process inspection from raw materials to finished products. Each batch is tested and traceable, ensuring safety, stability, and compliance with international requirements.

• OEM Customization

We offer OEM capsule customization to meet market demands. Whether for dietary supplements or functional foods, we can help your brand provide stable, reliable products that meet market demands.

Applications of Spermidine

• Cosmetics

Spermidine effectively combats oxidative damage to the skin caused by ultraviolet radiation and environmental pollution, delaying photoaging. It reduces moisture loss and promotes the repair of damaged skin tissue. Therefore, it is commonly used in skincare and cosmetic products.

• Dietary Supplements

Spermidine can resist aging and delay cellular aging, improve cognitive function, and is widely used in dietary supplements. It is often available in capsule, tablet, oral liquid, or powder form, and is often synergistically combined with ingredients such as PQQ, NMN, and astaxanthin to enhance anti-aging effects.

• Animal Feed

In the field of veterinary pharmaceutical raw materials, spermidine helps improve digestive function by regulating the balance of intestinal flora, promoting mucosal repair, and assisting in digestion. As a food additive, spermidine can enhance the antioxidant capacity of food and extend shelf life.

• Pharmaceuticals

Spermidine hydrochloride is used in the pharmaceutical field as a vasodilator for the treatment of hypertension and heart disease.

Wheat Germ Extract Spermidine Powder High Quality Supplier And Manufacturer

Green Spring is a professional cosmetic ingredient supplier with a dedicated R&D team focused on discovering, refining, and testing the various components needed for finished cosmetic products. The company boasts an independent R&D center that meets international standards and has a team with 26 years of R&D experience.

We offer a wide variety of active and functional cosmetic ingredients, all of which have undergone rigorous scientific testing to verify their efficacy and ensure purity and effectiveness, helping companies build brands and develop market strategies.

Leveraging our extensive cosmetic knowledge and strong scientific capabilities, we continuously introduce innovative ingredients to ensure consistent product efficacy. Our ingredients offer antibacterial, antipruritic, moisturizing, anti-allergic, whitening, spot-removing, sun-protective, and anti-inflammatory benefits.

How to buy Wheat Germ Extract Spermidine Powder ?

Just send an email to sales@greenspringbio.com, or submit your needs in the form at the bottom, we are always at your service!